Orinase-Met 1/500mg

Glimepiride is a medium-to-long-acting sulfonylurea antidiabetic drug that works by stimulating insulin release from pancreatic beta cells by closing the ATP-sensitive potassium channel. It is approximately 30 times more potent than sulfonylurea in stimulating insulin release. Metformin Hydrochloride, on the other hand, is a simple glucose-lowering agent that belongs to the biguanide class of drugs. It works by reducing glucose absorption in the intestine, reducing glucose production in the liver, and increasing glucose uptake and utilization in muscles. Glimepiride and Metformin Hydrochloride are both commonly prescribed drugs for type-2 diabetes. They work by reducing glucose levels in the blood, which can help reduce the risk of comorbidities linked with diabetes like neuropathy, kidney damage, and blindness. These two drugs offer complementary mechanisms of action, which means they work in different ways to manage diabetes effectively. As such, they are commonly co-prescribed to manage diabetes mellitus.