Azomax (200mg) Oral Suspension

Azithromycin is a macrolide antibiotic that binds to the 50S ribosomal subunits of bacteria, inhibiting their protein synthesis. This binding prevents the movement of tRNA peptidyl molecules, causing the inhibition of peptide chain elongation and termination of protein synthesis. Due to its high concentrations in the respiratory, genital, and urinary tracts, azithromycin is effective in treating bacterial infections specifically in these areas. Mid-infrared spectroscopy has shown that azithromycin binds to the 50S subunit of ribosomes and interferes with the translocation step, crucial for peptide chain synthesis. It is considered a functional analog to erythromycin but has a broader spectrum against gram-negative organisms and improved resistance profile. The mechanism of action of azithromycin is based on its binding to the ribosome and the inhibition of the translocation of peptidyl-tRNA, a critical step in protein synthesis. It is this interference with protein synthesis that leads to the inhibition of bacterial growth and replication. Given its broad distribution and mechanism of action, azithromycin is effective in treating various infections caused by different types of bacteria.